The Wellness Blog

Program Your Genes for Health with “The Forgotten B Vitamin"

Posted by US Wellness Meats on Fri, Oct 12, 2012 @ 09:35 AM

By: Kelley Herring, Healing Gourmet

FoodThere is a critical nutrient that can help your body detoxify. It can help you absorb more nutrients from your diet. It can prevent fat from accumulating in your liver. It helps your cells to communicate. It can reduce stress levels. Perhaps most importantly, it can even change your genetic expression to promote health and protect against disease.

But here’s the thing… you’re probably not getting enough of it. And if you happen to be a vegetarian, you’re almost certainly deficient in this vital compound.

In fact, according to the Institute of Medicine only 10% of Americans consume an “adequate” amount of this nutrient.

The compound I’m talking about is choline. It has also been called…

The Forgotten B Vitamin

Choline was first discovered in the 1930’s. It was originally studied for its ability to prevent fat and cholesterol from building up in the liver. But that’s not all choline does. Not by a long shot.
It also gives our cell membranes the ability to transfer both water-soluble and fat-soluble molecules. Without choline, lipid-soluble nutrients could not get into our cells. Likewise, waste products could not pass out. This causes nutrient depletion and toxic buildup at the cellular level.

Another unique aspect of choline is that it contains chemical structures called methyl groups. These components help cells to communicate with each other. They are also used by the body to turn genes on and off. They help produce neurotransmitters. And they have been shown to reduce inflammation and boost detoxification.

It’s no wonder that adequate “methylation” within your body reduces the risk of almost every chronic illness including cancer, heart disease, depression, Alzheimer’s and more.

And that’s why a deficiency of choline is bad news for your health. It is a vital component of every human cell. Not surprisingly, it is also critical during pregnancy and fetal development. It has been shown to prevent birth defects (like spina bifida) and to promote healthy brain development.

But that’s not the only way it helps mom and baby…

New research, published in The FASEB Journal, found that choline can lower levels of stress. The researchers found that pregnant women who ate 930 mg of choline per day had 33% lower levels of cortisol compared to women who ate only 430 mg daily.

Cortisol is known as the “stress hormone.” And research shows that babies who are exposed to high levels in the womb have an increased risk of type-2 diabetes, high blood pressure and stress-related illness later in life.

Is it Possible to Program Your Children’s (and Their Children’s) Health?

What’s even more interesting is that the dietary effects of choline don’t just affect the health of unborn babies. It has the potential to affect future generations as well.

The researchers found that women who consumed more choline switched on genes that beneficially affect hormone production in the fetus. The genes that were switched on were those that affect the HPA axis. To put it simply, this is the “motherboard” of hormone production.

The field of epigenetics studies how the foods (and chemicals) you ingest today can impact not only your own health, but also the health of your progeny. And it’s not because genetic mutations are passed down (although that can happen). Instead, it refers to how genes express themselves to promote health… or disease.

Better Diet Today, Healthier Genes Tomorrow

The great news is that you can influence how those genes are expressed. This is true even if you have inherited genes that would otherwise increase your risk of disease. And the best way to promote healthy genetic expression is to avoid chemicals and other contaminants and give your body the nutrients it needs.

And one nutrient that is critical is choline…

So, how much do you need and how do you get more of it in your diet?

The Institute of Medicine (IOM) recommends that women consume at least 425 mg daily. They recommend that men and breastfeeding women consume 550 mg daily. However, it’s important to note that adequate intake levels are only minimums. They do not represent the therapeutic amounts seen in studies. For example, the women in the FASEB study were receiving nearly twice the IOM’s recommendation for choline.

The richest sources of this vital nutrient include liver, beef, eggs, poultry and seafood. Here is the average choline content in some of these foods:

•    Beef liver (3 oz/355 mg)
•    Sardines (3 oz/188 mg)
•    Eggs (1 large/172 mg)
•    Beef, cooked (4 oz/124mg)
•    Chicken & Turkey (4 oz/97 mg)
•    Scallops & Scallops (4 oz/92 mg)

Unfortunately, most plant foods contain very little choline, so vegetarians may be at risk for deficiency. The richest plant sources are collards, Brussels sprouts, broccoli, crimini mushrooms, asparagus and cauliflower. These foods provide anywhere from 17-60 mg per cup.

Enjoy a wide variety of choline-rich foods to optimize your genes and help prevent chronic disease. Because choline is stable at high temperatures, you can enjoy your favorite foods cooked without reducing its concentration or action.


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ED NOTE: Kelley Herring is the Founder and Editor of Healing Gourmet – the leading provider of organic, sustainable recipes and meal plans for health and weight loss. Be sure to grab Eating Clean & Saving Green: Your Guide to Organic Foods on a Budget and Eat Your Way Into Shape: Flip Your Body’s Fat Blasting Switch and Melt 12 Pounds in 2 Weeks (includes a delicious 7 day meal plan!). Claim your free copies here...

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REFERENCES

1.    Jiang X, Yan J, West AA, Perry CA, Malysheva OV, Devapatla S, Pressman E, Vermeylen F, Caudill MA. Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans. FASEB J. 2012 Aug;26(8):3563-74. Epub 2012 May 1.
2.    Detopoulou P, Panagiotakos DB, Antonopoulou S, Pitsavos C, Stefanadis C. Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study. Am J Clin Nutr. 2008 Feb;87(2):424-30. 2008. PMID:18258634.
3.    Zeisel SH. Choline and phosphatidylcholine. In Shils M et al. (Eds). Nutrition in Health and Disease. Ninth Edition. Williams & Wilkins, Baltimore, 1999;513-523. 1999.
4.    Zeisel SH, Blusztajn. Choline and human nutrition. Ann Rev Nutr 1994;14:269-271. 1994.
5.    Zeisel SH. Is there a new component of the Mediterranean diet that reduces inflammation?. Am J Clin Nutr. 2008 Feb;87(2):277-8. 2008. PMID:18258614.
6.    Zeisel SH, Mar MH, Howe JC, Holden JM. Concentrations of choline-containing compounds and betaine in common foods. J Nutr 2003;133(5):1302-1307.
7.    Li Q, Guo-Ross S, Lewis DV, Turner D, White AM, Wilson WA, Swartzwelder HS. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. J Neurophysiol. 2004 Apr;91(4):1545-55. Epub 2003 Nov 26.
8.    Oregon State University, Linus Pauling Institute, Choline

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